Having only one kidney can raise concerns about an individual’s lifespan, taking into account the crucial role that kidneys play in maintaining bodily functions. However, studies and medical literature indicate that living with one kidney is generally safe and does not notably impact life expectancy or overall health. In fact, countless people are born with just a single functioning kidney, while others may have one removed due to donation or medical reasons. Provided that the remaining kidney is healthy and fully functional, it can compensate for the absence of the other without causing significant harm. Heterogeneous factors such as age, lifestyle choices, existing health conditions, and access to proper healthcare remain prominent determinants of an individual’s longevity. Therefore, a person with only one kidney should focus on maintaining a healthy lifestyle, including regular exercise, a balanced diet, adequate hydration, and regular check-ups to ensure optimal renal function and overall well-being.